Position: Academic StaffTelephone: 0216 578 0000-1611E-posta: email@example.comÇalışma Türü: Tam ZamanlıAkademikResumeResearch Interests Drug Design & Discovery Organic Synthesis Biography BSc. Yeditepe University, Pharmacy, 2007 PhD. Yeditepe University, Pharmaceutical Chemistry, 2012 Courses GivenOrganic Chemistry II+Lab.IIPharmaceutical Chemistry II+Lab.IIPharmaceutical Chemistry IIIPharmaceutical Chemistry I+Lab.I PublicationsPapers Beyer M, Henninger SJ, Haehnel PS, Mustafa AM, Gurdal E, Schubert B, Christmann M, Sellmer A, Mahboobi S, Drube S, Sippl W, Kindler T, Krämer OH, Identification of a highly efficient dual type I/II FMS-like tyrosine kinase inhibitor that disrupts the growth of leukemic cells. Cell Chemical Biology, 2021; https://doi.org/10.1016/j.chembiol.2021.10.011. Turgutalp B, Uslu M, Helvacioglu Sinem, Charehsaz M, Gurdal EE, Sippl W, Kocabas F, Yarim M, Lead Optimization and Structure-Activity Relationship Studies on Myeloid Ecotropic Viral Integration Site 1 Inhibitor. Journal of Medicinal Chemistry, 2021; 64(19):14448-14464. Koksal M, Dedeoglu-Erdogan A, Bader M, Gurdal EE, Sippl W, Reis R, Ozgurbuz M, Sipahi H, Celik T. Design, synthesis and molecular docking of novel 3,5-disubstituted-1,3,4-oxadiazole derivatives as iNOS inhibitors. Archiv der Pharmazie, 2021; 354, e2000469. Güneş SS, Yeşil C, Gurdal EE, Korkmaz EE, Yarım M, Aydın A, Sipahi H. Primum non nocere: In silico prediction of adverse drug reactions of antidepressant drugs. Computational Toxicology, 2021; 18: 100165. Wurzlbauer A, Rüben K, Gürdal E, Chaikuad A, Knapp S, Sippl W, Becker W, Bracher F. How to separate kinase inhibition from undesired monoamine oxidase α inhibition-the development of the DYRK1A inhibitor AnnH75 from the alkaloid harmine, Molecules, 2020; 25, 5962. Alhusadi NA, Turgutalp B, Deniz I, Turkoz Acar E, Sipahi H, Yarim M, Gurdal EE. Synthesis, antimicrobial, antioxidant and molecular docking studies on novel 6-methoxybenzothiazole-piperazine derivatives with propanamide chain, Current Topics in Medicinal Chemistry, 2020; 20(19): 1729-1737. Ozyazici T, Gurdal EE, Orak D, Sipahi H, Ercetin T, Gulcan HO, Koksal M. Synthesis, anti-inflammatory activity and molecular docking studies of some novel Mannich bases of the 1,3,4-oxadiazole-2(3H)-thione scaffold, Archiv der Pharmazie, 2020; 353(7): e2000061. Bobtaina E, Gurdal EE, Durmaz I, Cetin-Atalay R, Yarim M. Synthesis and cytotoxicity studies on novel piperazinylacetamides, Letters in Drug Design & Discovery, 2019; 16: 45-51. Gurdal EE, Turgutalp B, Gulcan HO, Erçetin T, Sahin MF, Durmaz I, Cetin-Atalay R, Nguyen QD, Sippl W, Yarim M. Synthesis of novel benzothiazole-piperazine derivatives and their biological evaluation as acetylcholinesterase inhibitors and cytotoxic agents, Anti-Cancer Agents in Medicinal Chemistry, 2017; 17: 1837-1845. Charehsaz M, Gurdal EE, Helvacıoğlu S, Yarım M. Toxicological evaluation of benzothiazole derivatives carrying piperazine ring, Marmara Pharmaceutical Journal (Journal of Research in Pharmacy), 2017; 21(2):243-250. Gurdal EE, Yarim M, Comparison of separation performance of polysaccaride-based chiral stationary phases in enantioseparation of 1-(4-chlorobenzhydryl)piperazine benzamide derivatives by HPLC, Journal of Analytical Chemistry, 2017; 72(2): 213-216. Gurdal EE, Durmaz I, Cetin-Atalay R, Yarim M, Cytotoxic activities of some benzothiazole-piperazine derivatives, Journal of Enzyme Inhibition & Medicinal Chemistry, 2015; 30(4): 649-654. Gurdal EE, Buclulgan E, Durmaz I, Cetin-Atalay R, Yarim M, Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives, Anti-Cancer Agents in Medicinal Chemistry, 2015; 15: 382-389. Gurdal EE, Durmaz I, Cetin-Atalay R, Yarim M, Synthesis and cytotoxicity studies of novel benzhydrylpiperazine carboxamide and thioamide derivatives, Journal of Enzyme Inhibition & Medicinal Chemistry, 2014; 29(2): 205-214. Gurdal EE, Yarim M, Durmaz I, Cetin-Atalay R, Cytotoxic activities of some novel benzhydrylpiperazine derivatives, Drug Research, 2013; 63(3): 121-128. Us D, Berk B, Gurdal E, Aytekin N, Kocagoz T, Caglayan B, Kurnaz IA, Erol DD, Mannich base derivatives of 3-hydroxy-6-methyl-4h-pyran-4-one with antimicrobial activity, Turkish Journal of Chemistry, 2010; 34: 447-456. Us D, Gurdal E, Berk B, Öktem S, Kocagoz T, Caglayan B, Kurnaz IA, Erol DD, 4H-Pyran-4-one derivatives: Leading molecule for preparation of compounds with antimycobacterial potential, Turkish Journal of Chemistry, 2009; 33: 803-812.