Filiz Esra ÖNEN BAYRAM | Faculty of Pharmacy

Position:

Academic Staff

Phone:

02165780000-3768

E-Mail:

esra.bayram@yeditepe.edu.tr

Time:

Full Time

Akademik

Resume

Research Interest

Small-molecule synthesis
Anticancer drug development
Heterocyclic derivatives
Combinatorial chemistry

Biography

BA: 2003 Ecole Nationale des Industries Chimiques, Nancy, France

MS: 2003 Ecole Nationale des Industries Chimiques, Nancy, France and Universite Pierre et Marie Curie, Paris, France

PhD. 2007 Universite Pierre et Marie Curie Paris, France

Courses Given

Pharmaceutical Chemistry I+Lab.I

Graduation Project I

Pharmaceutical Organic Chemistry I

Graduation Project II

Publications

Papers

Önen Bayram FE, Sipahi H, Acar ET, Kahveci Ulugöl R, Buran K, Akgün H. The cysteine releasing pattern of some antioxidant thiazolidine-4-carboxylic acids. Eur J Med Chem. 2016 May 23;114:337-44.

Charehsaz M, Onen-Bayram FE, Sipahi H, Buran K, Giri AK, Aydin A. Evaluation of the mutagenic and genotoxic effects of the ALC67 thiazolidine compound in Salmonella strains and human lymphocytes in vitro. Hum Exp Toxicol. 2015 Dec 13. pii: 0960327115621365.

Onen Bayram F Esra, Sipahi Hande, Akgün Hülya (2015). Acetylenic antiflates as anticancer agents. Pteridines. 2015; 26 (3): 85-92. DOI: 10.1515/pterid-2015-0006

Onen Bayram F Esra, Buran Kerem, Durmaz Irem, Berk Barkın, Cetin Atalay Rengul (2015). 3- Propionyl-thiazolidine-4-carboxylic acid ethyl esters: a family of antiproliferative thiazolidines. MedChemComm, 6, 90-93

Onen-Bayram EF, Durmaz I, Scherman D, Herscovici J, Cetin-Atalay R. (2012) A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells, Bioorg. Med. Chem., 20(17), 5094-5104. (2 citations)

lalia I., Beauvineau C., Beauviere S., Onen E., Aufort M., Beauvineau A., Khaba E., Herscovici J., Meganem F., Girard C. (2010) Automated Synthesis of a 96 Product-Sized Library of Triazole Derivatives Using a Solid Phase Supported Copper Catalyst, Molecules, 15(5), 3087-3120. (9 citations)

Onen E , Boum Y., Jacquement C., Spanedda M.V., Jaber N., Scherman D., Myllykallio H., Herscovici J. (2008) Design, synthesis and evaluation of potent thymidylate synthase X inhibitors, Bioorg. Med. Chem. Lett., 18(12), 3628-3631. (14 citations)

Girard C., Onen E., Aufort A., Beauviere S., Edmond S., Herscovici, J. (2006) Reusable polymer-supported catalyst for the [2+3] Huisgen cycloaddition in automation protocols, Org. Lett., 8(8), 1689-1692. (135 citations)

Girard C., Onen E., Aufort A., Beauviere S., Edmond S., Herscovici, J. (2006) Reusable polymer-supported catalyst for the [2+3] Huisgen cycloaddition in automation protocols, ChemInform, 37(35), 1689-1692.