Hülya AKGÜN

Position:

Academic Staff

Telephone:

02165780000-1839

E-posta:

hakgun@yeditepe.edu.tr

Çalışma Türü:

Tam Zamanlı

Akademik

Resume

Research Interest

Synthesis of new active molecules
NMR spectroscopy

Biography

BA: Hacettepe University, Pharmacy

MS: Hacettepe University, Pharmaceutical Chemistry

PhD: Hacettepe University, Pharmaceutical Chemistry

Courses Given

Graduation Project I

Graduation Project II

Pharmaceutical Chemistry II+Lab.II

Publications

Papers

Yıldız Y, Akgün H, Sipahi H, Deniz İ, Berk B. (2019) Synthesis, Characterization and Potential Anticancer and Antimicrobial Activities of New Phthalamide Derivatives. Pharmaceutical and Chemical Journal. 6(2): 72-83 .
Akgün H, Kaya B, Mulazim Y, Kesanli B, Sipahi H, Kadıoğlu B, Berk B, Biltekin S N. (2019) Synthesis and Biological Activity Studies of Substituted N-(1,3-Dioxohexahydro-2H-Isoindol-2-yl) Benzenesulfonamide Derivatives. Pharmaceutical and Chemical Journal. 6(2):91-102.
Yılmaz D U, Terlemez H, Turnalar T, Sipahi H, Kadioglu B, Deniz I and Akgun H.( 2016) Synthesıs and pharmacologıcal actıvıtıes of Some novel N,N′-disubstituted urea dervatives. International Journal of Research ın Pharmacy and Chemıstry. 6(2), 363-371.
Akgün H, Yılmaz D U, Çetin A R and Gözen D. (2016) A series of 3-substituted-2,4(1H,3H)-quinazolidone Derivatives: Synthesis and biological evoluation as potential Anticancer Agents. Letters in Drug design & discovery 13: 64-76.
Bayram F E Ö, Sipahi H, Acar E T, Ulugöl R K, Buran K, Akgün H. (2016) The cysteine releasing pattern of some antioxidant thiazolidine-4-carboxylic acids. European Journal of Medicinal Chemistry. 3: 337–344.
Bayram F E Ö, Sipahi H and Akgün H. (2015) Acetylenic antifolates as anticancer agents Pteridines 26(3): 85-133.
Akgün H, Karamelekoglu I, Berk B, Kurnaz I, Sarıbıyık G, Öktem S, Kocagöz T. (2012) Synthesis and antimycobacterial activity of some phthalimide derivatives. Bioorganic & Medicinal Chemistry. 20: 4149–4154.
Akgün H, Karamelekoğlu İ. (2010) Recent Developments of Thalidomide Derivatives Possessing Anti-Inflammatory Activity. Anti-Inflammatory Anti-Allergy Agents in Medicinal Chemistry 9: 71-81.
Akgün H, Berk B, Erol D D, Mercanoğlu G,. Bayrak ÖF, Çağlayan B, Dedeağaç A,. Kurnaz IA.(2009) Nitric Oxide Derivatives of [(2-chloethyl)ureido]Benzoic acid Esters as PotentialAntineoplastic Agents. Turk. J. Chem. 33: 107-121.
Berk B, Akgün H, Erol K, Sırmagül B, Zhan-Guo G,. Jacobson K A^. (2005) New 8-substitutedxanthine derivatives as potent bronchodilators. IL FARMACO. 60: 974-980.
Hudlicky T, Rinner U, Gonzalez D, Akgün H, Schilling S, Siengalewicz P, Martinot T A and Pettit R.(2002) Total Synthesis and Biological Evaluation of Amaryllidaceae Alkaloids: Narciclasine ent-7-Deoxypancratistatin, Regioisomer of 7-Deoxypancratistatin and Truncated Derivatives. J. of Organic Chemistry. 67(25) : 8726-8743.
Akgün H, Hudlicky T. (2002) Total Synthesis of ent-Conduramine A and ent-7-Deoxypancratistatin.Tetrahedron Lett., 40 (16):3081-3084.
Akgün H, Balkan A, Günay Ş,. Erol K, Boydağ S. (1997) New Some 7-Aryloxyalkyltheophyllines as Bronchodilators, Eur. J. of Med. Chem. 32: 175-179.

Book Chapters

H. Akgün, A. Balkan, A. A. Bilgin, Ü. Çalış, S. Dalkara, H. Erdoğan, D.D. Erol, M. Etan, F. Özkanlı, E. Palaska, S. Saraç, C. Şafak Farmasötik Kimya I, II Irmak Matbaası Ankara 2000.
H. Akgün, A. Balkan, A. A. Bilgin, Ü. Çalış, S. Dalkara, H. Erdoğan, D.D. Erol, M. Etan, F. Özkanlı, E. Palaska, S. Saraç, C. Şafak Farmasötik Kimya I, II Irmak Matbaası, İkinci Baskı Ankara 2004.

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Hülya AKGÜN

Akademik