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Course Code: 
PHAR 575
Course Type: 
Elective
P: 
2
Lab: 
0
Credits: 
2
ECTS: 
3
Course Language: 
English
Course Coordinator: 
Hasan KIRMIZIBEKMEZ
Courses given by: 
Hasan KIRMIZIBEKMEZ
Course Objectives: 
The aim of this course is to provide theoretical information about the interactions between the herbal drugs and conventional drugs. The lectures will cover the recent literatures and case-reports concerning the herb-drug interactions. Further, the responsibility of pharmacist for preventing these interactions will also be discussed in detail.
Course Content: 

Recent papers and case-reports reporting the interaction of frequently used herbal drugs in Phytotherapy with conventional drugs will be compiled and discussed.

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D:False and troth, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

Programme learning outcomes

Teaching Methods

Assessment Methods

1) Knows the importance of herb-drug interactions. Knows the mechanisms of herb drug interactions

1,2

1,2,3

A,C

2) Knows how to prevent herb drug interactions and takes responsibilities

1,6

1,2,3

A,C

3) Defines the quality standards in herbal preparations

2,10

1,2,3

A,C

4) Knows the effects of herbs such as Hypericum perforatum, Ginkgo biloba, Panax ginseng, Echinacae, garlic as well as their interactions with the prescribed drugs.

1,2

1,2,3

A,C

5) Knows how to find scientific papers about the interaction of herbal teas, grape fruit juice, vitamins and minerals with the conventional drugs as well as the herb-drug interactions in oncology and surgery. Has the ability to review these data and present it.

1,2,5,7,8

1,2,3,4

A,C,H
 

Course Flow

COURSE CONTENT

Week

Topics

Study Materials

1

  Introduction to herbal drugs, problems with herbal drugs

Lecture notes

2

Methods used for the evaluation of herb-drug interaction, mechanisms of  herb-drug interactions, advers effects of herbal drugs

Lecture notes

3

Mechanisms of drug- drug and herb drug interactions

 Cytochrome P450 enzyme family

Lecture notes

4

SAINT JOHN'S WORT: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

5

GINKGO and GINSENG: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

6

Echinacea and devil’s claw: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

7

Garlic and flaxseed: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

8

Saw Palmetto and Kava: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

9

Valerian, milk thistle, feverfew: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

10

Black Cohosh, licorice: Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

11

Possible side effects and herb drug interactions of anthraquinone-containing drugs such as senna, buchthorn

Lecture notes

12

Chaste tree, ispaghula seed:   Chemical composition, drug interactions, possible mechanism of interactions and results of interaction

Lecture notes

13

Interactions of  grapefruit juice with conventional drugs

Literature survey and review

14

Interactions of  herbal teas with conventional drugs

Literature survey and review

15

Herb-drug interactions in oncology and in surgery

Literature survey and review

16

Interactions of vitamins and minerals with conventional drugs

Literature survey and review
 

Recommended Sources

RECOMMENDED SOURCES

Textbook

  

Additional Resources

Elecronic data base: Web of Science, PubMed, Scopus
 
 

 

Material Sharing

MATERIAL SHARING

Documents

Lecture notes via COADSYS/MOODLE  

Assignments

Relevant papers

Exams

  
 

Assessment

ASSESSMENT

IN-TERM STUDIES

NUMBER

PERCENTAGE

Mid-terms

1

50

Assignment

1

50

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 

50

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

50

Total

 

100
 
 

COURSE CATEGORY

Elective
 

Course’s Contribution to Program

COURSE'S CONTRIBUTION TO PROGRAM

No

Program Learning Outcomes

Contribution

1

2

3

4

5

1

Has national and international up-to-date, theoretical and applied knowledge in the field of pharmacy.

      

X

  

2

Defines problems related to the profession, collects data, evaluates its accuracy and reliability, develops evidence-based solutions, shares them with healthcare professionals, makes necessary explanations to other people.

      

 

X

3

Communicates accurately and effectively in accordance with cultural and ethical values with all relevant professional groups, especially those working in the field of health, and all segments of society, using information and communication technologies.

      

X

 

4

Takes into account the law and ethics when dealing with public health issues.

    

X

 

 

5

Acts as a pharmacist with high career awareness, self-confidence, leadership spirit, who is prone to teamwork, entrepreneurial, productive and able to manage financial resources.

  

X

  

 

 

6

Based on the principle of pharmaceutical care, Acts as an easily accessible health consultant with a patient-oriented approach and plays an active role in constantly informing the society.

      

X

 

7

Improves his/her knowledge by participating in in-service training and activities in line with the needs of the century and society, takes part in the professional development of colleagues and adopts the lifelong learning principle.

  

 

 

X

 

8

Suggests and manages multidisciplinary / interdisciplinary research and development projects related to pharmaceuticals, cosmetics, medical devices and shares their results.

  

 

 

X

 

9

Applies knowledge and skills for the benefits of the society taking part in social responsibility projects.

    

X

    

10

Fulfills the requirements of quality management systems using the theoretical and applied knowledge acquired in the field.

    

x

 

 
 

ECTS

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

16

2

32

Hours for off-the-classroom study (Pre-study, practice)

16

2

32

Mid-terms

1

1

1

Assignment

1

2

2

Final examination

1

1

1

Total Work Load

    

68

Total Work Load / 25 (h)

 

 

2.7

ECTS Credit of the Course

 

 

3
 
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