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Course Code: 
PHAR 318
Course Period: 
Spring
Course Type: 
Core
P: 
2
Lab: 
0
Credits: 
2
ECTS: 
3
Course Language: 
English
Course Objectives: 
This lecture aims to educate students about chemical properties, synthesis, structure activity relationships and metabolism pathways of various drugs in specific pharmacological classes.
Course Content: 

Theoretical part: Chemical properties, synthesis, structure activity relationships and metabolism pathways of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

Laboratory applications:

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion
Course Evaluation Methods: 
A:Written exam

Vertical Tabs

Course Learning Outcomes

Course Learning Outcomes

Program Learning Outcomes*

Teaching Methods**

Assessment Methods***

1) Student can name drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity according to IUPAC nomenclature.

7,14

1,2,3

A

2) Student knows chemical properties of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

7,14

1,2,3

A

3) Student knows synthesis methods of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

7,14

1,2,3

A

4) Student knows action mechanism of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

7,14

1,2,3

A

5) Student knows structure activity relationships of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

7,14

1,2,3

A

6) Student knows biotransformation pathways of drugs about endocrine system, non-steroidal antiinflammatory drugs, antihistaminics, vitamins, diagnostic agents, men’s & women’s health, obesity.

7,14

1,2,3

A

 
 

Course Flow

Week

Topics                                     

Preliminary Preparation

1)

Hormones: Thyroid Function and Thyroid Drugs

---

2)

Hormones: Adrenocorticoids

---

3)

Hormones: Adrenocorticoids

---

4)

Hormones: Insulin and Drugs Used to Treat Diabetes

 

5)

Hormones: Calcium Homeostasis

---

6)

Non-Steroidal Antiinflammatory Drugs

---

7)

Non-Steroidal Antiinflammatory Drugs

---

8)

Antihistamines and Related Antiallergic and Antiulcer Agents

---

9)

Asthma and Chronic Obstructive Pulmonary Disease

---

10)

Vitamins

---

11)

Diagnostic Agents

---

12)

Men’s Health

---

13)

Women’s Health

---

14)

Nutrition and Obesity

---

 
 

Recommended Sources

Class Notes

Class notes

Additional References

  • 1. David A. Williams, Thomas L. Lemke ‘Foye’s Principle of medicinal Chemistry’ 7th edition, Williams & Wilkins, Phyladelphia (2012)
  • 2. H.Akgün, A. Balkan, A.Bilgin, Ü. Çalış, N. Gökhan, S. Dalkara, H. Erdoğan, D. Demir, M. Ertan, F. Özkanlı, E. Palaska, S. Saraç, C. Şafak, B. Tozkoparan, ‘Farmasötik Kimya’ İkinci baskı, Hacettepe, Ankara (2004)
  • 3. John H. Block, John M. Beale Jr., ‘Wilson and Giswolds textbook of organic madicinal and pharmaceutical chemistry’ 11th edition, Baltimore Williams & Wilkins, (2004)
 
 

Material Sharing

Documents

Power point presentation

 

 

 

Assessment

IN-TERM STUDIES

NUMBER

PERCENTAGE OF CONTRIBUTION

Midterm Exam

1

40

Final Exam

1

60

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 

60

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

40

Total

 

100

 

 

COURSE CATEGORY

Compulsatory

 
 

Course’s Contribution to Program

No

Program Learning Outcomes (LO)

Contribution Level*

1

2

3

4

5

1

Acquire skills needed to practice the profession of pharmacy in either a Turkish or an English language setting.

       

X

2

Being equipped to access current theoretical and applied knowledge, keeping abreast of new developments, and possessing the critical faculties enabling an accurate and reliable interpretation and assessment of this information.

     

X

 

3

Having the capacity to apply the skills acquired in the field of pharmaceutical science. Possessing the ability to harness his/her acquired knowledge in order to function as a highly accessible health counsellor, providing a ready source of clinically relevant, health-related information to the general public.

     

X

 

4

Keeping abreast of and being equipped to apply the fundamental pharmaceutical and health science principles which guide future developments in modern technology, and being able to share these experiences and skills with colleagues through participation in professional development education seminars.

       

X

5

Knowing how to assess risks arising from the use of drugs and other chemicals and those risks potentially encountered during laboratory practice.

   

X

   

6

Acquiring the skills and knowledge needed to interpret findings obtained through quantitative and qualitative measurements, and thus reach valid, scientific conclusions based on this data. 

   

X

   

7

Being able to compound pharmaceutical products while being knowledgeable about their clinical application, interactions, side effects and risks  and apply in proper manner.

       

X

8

Being competent to conduct and manage research and development projects, and share experimental outcomes.

       

X

9

Be competent to accurately and intelligibly communicate clinically relevant information to patients concerning prescription items and other pharmaceutical products.  

   

X

   

10

Being able to function in a multidisciplinary environment. Possessing the skill to collaborate and establish lines of communication with other professionals, while developing their own professional competency through participation in relevant continuing education activities.

     

X

 

11

Being able to play a role in projects which fulfills the profession’s societal responsibilities. Participating in professional activities and undertaking duties in a manner which reflects an awareness of and sensitivity to environmental issues.

     

X

 

12

Being capable of opening a community pharmacy, practicing in a hospital pharmacy setting, and offering service in any field related to drugs, cosmetics, medical  and/or plant-derived products. Able to play an active role in his/her own personal professional development, as well as that of colleagues and pharmaceutical students.

   

X

   

13

Able to play a role in issues related to public health as a member of the health care team while being cognizant of and able to fulfill legal and professional requirements and maintain ethical standards. 

 

X

     

14

Is knowledgeable of and equipped to manage the planning, development, compounding and quality control analysis of naturally occurring and synthetic medicines, while also being aware of the processes related to these products’ absorption, distribution, metabolism and excretion from the body.

       

X

 
 

ECTS

Activities

Quantity

Duration
(Hour)/week

Total
Workload
(Hour)

Course Duration (Including the exam week)

14

2

28

Hours for off-the-classroom study (Pre-study, practice)

14

2

28

Midterm Examination

1

7

7

Final  Examination

1

12

12

Total Work Load

 

 

75

Total Work Load / 25 (h)

 

 

3.0

ECTS Credit of the Course

 

 

3