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Course Code: 
PHAR 213
Course Period: 
Autumn
Course Type: 
Core
P: 
4
Lab: 
0
Credits: 
6
ECTS: 
6
Course Language: 
English
Course Coordinator: 
Filiz Esra ÖNEN BAYRAM
Courses given by: 
Hülya AKGÜN
Filiz Esra ÖNEN BAYRAM
Course Objectives: 
The main aim of these lectures is to provide students a strong tool that will be used to understand at a molecular level reactions occurring in biological systems. As a continuation of PHAR 114 Organic Chemistry I, the lectures will focus on the main organic functions encountered in biological systems. For each functionality their nomenclature, their physico-chemical properties and major chemical reactions associated with each family will be described.
Course Content: 

 

a) Theoretical Part:

 

Chemistry of Benzene: Electrophilic Aromatic Substitution; Alcohols and Phenols; Ethers and Epoxides; Thiols and Sulfides; Carbonyl Compounds; Carboxylic Acids and Nitriles; Carboxylic Acid Derivatives; Amines; Biomolecules-Carbonhydrates; Biomolecules-Aminoacids; Biomolecules-Lipids; Heterocycles and Nucleic Acids

 

b) Laboratory Practice:

 

Laboratory safety demonstration; Basic organic laboratory skills demonstration; Glassware demonstration; Yield calculation demonstration; Thin layer chromatography demonstration; Iodoform and Dermatole synthesis; Aspirin synthesis; Acetophenone synthesis; Acetanilide synthesis; Benzoin synthesis; Benzil synthesis; Diphenylhydantoin synthesis; Benzoic acid and Benzyl alcohol synthesis

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D:False and troth, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

Programme learning outcomes

Teaching Methods

Assessment Methods

1) Names compounds based on IUPAC nomenclature.

1,2,8

1,2,3

A,C

2) Knows synthesis of organic compounds.

1,2,8

1,2,3

A,C

3) Knows reactions of organic compounds.

1,2,8

1,2,3

A,C

4) Knows physicochemical properties of organic compounds.

1,2,8

1,2,3

A,C

5) Can synthesize organic compounds in the laboratory.

1,2,8

1,2,3

A,C

6) Knows various methods to isolate compounds from the reaction environment

1,2,8

1,2,3

A,C

7) Knows various methods to purify compounds after isolation.

1,2,8

1,2,3

A,C

8) Knows purity analysis methods such as melting point determination and thin layer chromatography.

1,2,8

1,2,3

A,C

9) Knows percentage yield calculation of purified compounds.

1,2,8

1,2,3

A,C
 
 

Course Flow

Week

Teorical Topics                                     

Lab content

Study Materials

1

Chemistry of Benzene: Electrophilic Aromatic Substitution

Laboratory safety; Basic organic laboratory skills; Glassware demonstration

  

2

Alcohols and Phenols

Yield calculation; Thin layer chromatography demonstration

  

3

Ethers and Epoxides

Iodoform and Dermatole synthesis

  

4

Thiols and Sulfides

Aspirin synthesis

  

5

Carbonyl Compounds

Acetophenone synthesis

  

6

Carboxylic Acids and Nitriles

Acetanilide synthesis

  

7

Carboxylic Acid Derivatives

Midterm

  

8

Amines

Benzoin synthesis

  

9

Midterm I

Benzil synthesis

  

10

Biomolecules-Carbonhydrates

Diphenylhydantoin synthesis

  

11

Biomolecules-Aminoacids

Benzoic acid and Benzyl alcohol synthesis

  

12

Biomolecules-Lipids

Make-up week

  

13

Heterocycles and Nucleic Acids

Problem solvation

  

14

Midterm II

Problem solvation

  

15

Summary and Discussion

Problem solvation

  
 
 

Recommended Sources

Textbook

Assoc. Prof. Esra Önen Bayram

Additional Resources

1. John McMurry,Organic Chemistry, 6th Ed, Thomson Brooks/Cole, USA (2004)

2. Solomons G., Fryhe J., Solomons Organic Chemistry, 10th Ed, Wiley, USA (2010)
 
 

Material Sharing

Documents

Documents shared on coadsys exam and/or Google Classroom platforms

Assignments

  

Exams

  
 
 

Assessment

IN-TERM STUDIES

NUMBER

PERCENTAGE

Midterm  Exam

2

60

Short Exam

    

Lab.

15

20

Lab final

1

20

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 1

40

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 1

60

Total

 

100
 

 

COURSE CATEGORY

Compulsary/Elective
 
 

Course’s Contribution to Program

No

Program Learning Outcomes

Contribution

1

2

3

4

5

1

Has national and international up-to-date, theoretical and applied knowledge in the field of pharmacy.

  

 

   x  

2

Defines problems related to the profession, collects data, evaluates its accuracy and reliability, develops evidence-based solutions, shares them with healthcare professionals, makes necessary explanations to other people.

  

 

   x  

3

Communicates accurately and effectively in accordance with cultural and ethical values with all relevant professional groups, especially those working in the field of health, and all segments of society, using information and communication technologies.

  

x

      

4

Takes into account the law and ethics when dealing with public health issues.

 x  

 

    

5

Acts as a pharmacist with high career awareness, self-confidence, leadership spirit, who is prone to teamwork, entrepreneurial, productive and able to manage financial resources.

 x  

 

    

6

Based on the principle of pharmaceutical care, Acts as an easily accessible health consultant with a patient-oriented approach and plays an active role in constantly informing the society.

 x  

 

    

7

Improves his/her knowledge by participating in in-service training and activities in line with the needs of the century and society, takes part in the professional development of colleagues and adopts the lifelong learning principle.

 x    

 

  

8

Suggests and manages multidisciplinary / interdisciplinary research and development projects related to pharmaceuticals, cosmetics, medical devices and shares their results.

X

        

9

Applies knowledge and skills for the benefits of the society taking part in social responsibility projects.

 x

 

      

10

Fullfills the requirements of quality management systems using the theoreticaland applied knowledge acquired in the field

 x

 

      
 
 

ECTS

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

16

4

64

Hours for off-the-classroom study (Pre-study, practice)

8

0.5

4

Midterm Exams

2

4

8

Lab. Applications

16

4

64

Hours for off-the-Lab. study (Pre-study, practice)

4

0.5

2

Lab. Midterm Exem

1

2

2

Lab. Final

1

4

4

Homework

 

 

 

Final

1

4

4

Total Work Load

 

 

152

Total Work Load / 25 (h)

 

 

6.08

ECTS Credit of the Course

 

 

6
 
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