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Position: 
Dean
Phone: 
02165780000-1839
Time: 
Full Time

Akademik

Resume

Research Interest

  • Synthesis of new active molecules
  • NMR spectroscopy

 

 

Biography

BA:  Hacettepe University, Pharmacy
MS: Hacettepe University, Pharmaceutical Chemistry
PhD: Hacettepe University, Pharmaceutical Chemistry
Courses Given
Publications
Papers
  1. Yıldız Y, Akgün H, Sipahi H, Deniz İ, Berk B. (2019) Synthesis, Characterization and Potential Anticancer and Antimicrobial Activities of New Phthalamide Derivatives. Pharmaceutical and Chemical Journal.  6(2): 72-83 .
  2. Akgün H, Kaya B, Mulazim Y, Kesanli B, Sipahi H, Kadıoğlu B, Berk B, Biltekin S N. (2019) Synthesis and Biological Activity Studies of Substituted N-(1,3-Dioxohexahydro-2H-Isoindol-2-yl) Benzenesulfonamide Derivatives. Pharmaceutical and Chemical Journal. 6(2):91-102.
  3. Yılmaz D U, Terlemez H, Turnalar T, Sipahi H, Kadioglu B, Deniz I and Akgun H.( 2016) Synthesıs and pharmacologıcal actıvıtıes of Some novel N,N′-disubstituted urea dervatives.  International Journal of Research ın Pharmacy and Chemıstry. 6(2), 363-371.
  4. Akgün H, Yılmaz D U, Çetin A R and Gözen D. (2016) A series of 3-substituted-2,4(1H,3H)-quinazolidone Derivatives: Synthesis and biological evoluation as potential Anticancer Agents.  Letters in Drug design & discovery 13: 64-76.  
  5. Bayram F E Ö,  Sipahi H,  Acar E T,  Ulugöl R K,  Buran K,  Akgün H. (2016) The cysteine releasing pattern of some antioxidant thiazolidine-4-carboxylic acids. European Journal of Medicinal Chemistry. 3: 337–344.
  6. Bayram F E Ö, Sipahi H and Akgün H. (2015) Acetylenic antifolates as anticancer agents Pteridines 26(3): 85-133.  
  7. Akgün H, Karamelekoglu I,  Berk B,  Kurnaz I, Sarıbıyık G, Öktem S,  Kocagöz T. (2012)  Synthesis and antimycobacterial activity of some phthalimide derivatives. Bioorganic & Medicinal Chemistry. 20: 4149–4154.
  8. Akgün H, Karamelekoğlu İ. (2010) Recent Developments of Thalidomide Derivatives Possessing Anti-Inflammatory Activity. Anti-Inflammatory Anti-Allergy Agents in Medicinal Chemistry 9: 71-81.
  9. Akgün H, Berk B, Erol D D, Mercanoğlu G,. Bayrak ÖF, Çağlayan B, Dedeağaç A,. Kurnaz IA.(2009) Nitric Oxide Derivatives of [(2-chloethyl)ureido]Benzoic acid Esters as PotentialAntineoplastic Agents. Turk. J. Chem. 33: 107-121.
  10. Berk B, Akgün H,  Erol K,  Sırmagül B, Zhan-Guo G,. Jacobson K A. (2005) New 8-substitutedxanthine derivatives as potent bronchodilators. IL FARMACO. 60: 974-980.
  11. Hudlicky T, Rinner U, Gonzalez D, Akgün H, Schilling S, Siengalewicz P, Martinot T A and Pettit R.(2002) Total Synthesis and Biological Evaluation of Amaryllidaceae Alkaloids: Narciclasine ent-7-Deoxypancratistatin, Regioisomer of 7-Deoxypancratistatin and Truncated Derivatives. J. of Organic Chemistry. 67(25) : 8726-8743.
  12. Akgün H, Hudlicky T. (2002) Total Synthesis of ent-Conduramine A and ent-7-Deoxypancratistatin.Tetrahedron Lett., 40 (16):3081-3084.
  13. Akgün H, Balkan A, Günay Ş,. Erol K, Boydağ S. (1997) New Some 7-Aryloxyalkyltheophyllines as Bronchodilators, Eur. J. of Med. Chem. 32: 175-179.
Book Chapters
  1. H. Akgün, A. Balkan, A. A. Bilgin, Ü. Çalış, S. Dalkara, H. Erdoğan, D.D. Erol, M. Etan, F. Özkanlı, E. Palaska, S. Saraç, C. Şafak Farmasötik Kimya I, II Irmak Matbaası Ankara 2000.        
  2. H. Akgün, A. Balkan, A. A. Bilgin, Ü. Çalış, S. Dalkara, H. Erdoğan, D.D. Erol, M. Etan, F. Özkanlı, E. Palaska, S. Saraç, C. Şafak Farmasötik Kimya I, II Irmak Matbaası, İkinci Baskı Ankara 2004.