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Course Code: 
PHAR 103
Course Period: 
Autumn
Course Type: 
Core
P: 
3
Lab: 
0
Credits: 
3
ECTS: 
4
Course Language: 
English
Course Objectives: 
This course is about understanding of basics of molecular and cellular biology and human genetics.
Course Content: 

 

a)Therotical part: Cell structure and functions of cell organels, structures and functions of DNA, RNA and proteins, the patterns of inheritance and genetic disorders and their repair mechanisms. Genetic diseases like cancer. Molecular biology and biotechnology application fields in medicine.

b) Laboratory applications

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D: True and False, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

The student will successfully

Programme learning outcomes

Teaching Methods

Assessment Methods

1)Explain the structures of the molecules involves in cell structure.

all

1,2,3,6

A,B,C,D,H

2) Explain the functions and structures of cell organells.

all

1,2,3,6

A,B,C,D,H

3) Explain the structures and synthesis of DNA, RNA and proteins

all

1,2,3,6

A,B,C,D,H

4) Explain genetic disorders and their repair mechanisms.

all

1,2,3,6

A,B,C,D,H

5) Explain the molecular mechanisms of single gene and multifactorial disorders and diseases.

all

1,2,3,6

A,B,C,D,H

6) Explain the application fields of molecular biology techniques and biotechnology in medical field.

all

1,2,3,6

A,B,C,D,H

7) Explain the use of molecular biology and genetic knowledge in diseases prevention and personolized medicine 

all

1,2,3,6

A,B,C,D,H

8) Consider ethical issues in applications of molecular biology and genetics in medicine

all

1,2,3,6

A,B,C,D,H

 
 

Course Flow

 

 

COURSE CONTENT

 

Week

Teorical Topics                                     

Lab

Study Materials

1

Introduction to Cell and Cell research

 

  Basic cell characteristics

2

Molecular Structures of Carbohydrates, Lipids, Proteins and Nucleic Acids

 

  The molecules of cells 

3

Structures of Cell and Cell Organels

 

Cell structures and functions

4

Cell Cycle and Cell Division

 

Cell Cycle

5

Structures and Functions of DNA and RNA

 

DNA, RNA

6

Transcription and Translation

 

Mechanisms of Transcription and Translation

7

Gene Expression and Control Mechanims

 

Gene Expression

8

Exam week

 

 

9

DNA Damage and Repair Mechanims

 

DNA repair mechanisms

10

Cancer and Cancer Prevention

 

Basics of cancer

11

Mendel’s Law

 

Patterns of inheritance

12

Single Gene and Multifactorial Genetic Disorders and Diseases

 

Inherited diseases

13

Gene Therapy and Stem Cells

 

Basics of gene therapy and stem cell research

14

Molecular Biology Techniques and Their Application in Medicine

 

Molecular Biology Techniques

15

FINAL EXAM

 

 

 
 

Recommended Sources

Textbook

Lecture Notes will be handed out to students

Additional Resources

  1. The Cell: A Molecular Approach, Fifth Edition by Geoffrey M. Cooper, Robert E. Hausman;   
  2. Molecular Biology of THE CELL, Fifth Edition by Bruce Alberts
  3. Medical Cell Biology by Steven R. Goodman
     
 
 

Material Sharing

Documents

Lecture topics related webpages will be given to students

Assignments

Three or four homeworks will be given during semester

Exams

Although number of exams is depends on course instructor, there will be at least one midterm exam and one final exam

 
 

Assessment

IN-TERM STUDIES

NUMBER

PERCENTAGE

Midterm  Exam

2

40

Final Exam

1

60

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 

60

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

40

Total

 

100

 

 

COURSE CATEGORY

Compulsary

 
 

Course’s Contribution to Program

No

Program Learning Outcomes

Contribution

1

2

3

4

5

 

1

Acquire skills needed to practice the profession of pharmacy in either a Turkish or an English language setting.

     

X

   

2

Being equipped to access current theoretical and applied knowledge, keeping abreast of new developments, and possessing the critical faculties enabling an accurate and reliable interpretation and assessment of this information.

     

X

   

3

Having the capacity to apply the skills acquired in the field of pharmaceutical science. Possessing the ability to harness his/her acquired knowledge in order to function as a highly accessible health counsellor, providing a ready source of clinically relevant, health-related information to the general public.

     

X

   

4

Keeping abreast of and being equipped to apply the fundamental pharmaceutical and health science principles which guide future developments in modern technology, and being able to share these experiences and skills with colleagues through participatation in professional development education seminars.

     

x

   

5

Knowing how to assess risks arising from the use of drugs and other chemicals and those risks potentially encounterd during laboratory practice.

     

X

   

6

Acquiring the skills and knowledge needed to interpret findings obtained through quantative and qualitative measurements, and thus reach valid, scientific conclusions based on this data. 

     

X

   

7

Being able to compound pharmaceutical products while being knowledgable about their clinical application, interactions, side effects and risks  and apply in proper manner .

     

X

   

8

Being competent to conduct and manage research and development projects, and share experimental outcomes.

       

X

 

9

Be competent to accurately and intelligibly communicate clincally relevant information to patients concerning prescription items and other pharmaceutical products.  

     

X

   

10

Being able to function in a multidisciplinary environment. Possessing the skill to collaborate and establish lines of communication with other professionals, while developing their own professional competency through participation in relevant continuing education activities.

       

x

 

11

Being able to play a role in projects which fulfills the profession’s societal responsibilities. Participating in professional activities and undertaking duties in a manner which reflects an awareness of and sensitivity to environmental issues.

       

X

 

12

Being capable of opening a community pharmacy, practicing in a hospital pharmacy setting, and offering service in any field related to drugs, cosmetics, medical  and/or plant-derived products. Able to play an active role in his/her own personal professional development, as well as that of colleagues and pharmaceutical students.

     

X

   

13

Able to play a role in issues related to public health as a member of the health care team while being cognizant of and able to fulfill legal and professional requirements and maintain ethical standards. 

       

X

 

14

Is knowledgable of and equipped to manage the planning, development, compounding and quality control analysis of naturally occuring and synthetic medicines, while also being aware of the processes related to these products’ absorption, distribution, metabolism and excretion from the body.

     

x

   
 
 

ECTS

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

16

3

48

Hours for off-the-classroom study (Pre-study, practice)

16

3

48

Midterm Exams

2

3

6

Short-exam (Quiz)

2

3

6

Homework

3

3

9

Final exam

1

10

10

Total Work Load

 

 

127

Total Work Load / 25 (h)

 

 

4.96

ECTS Credit of the Course

 

 

4