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Course Code: 
PHAR 413
Course Period: 
Autumn
Course Type: 
Core
P: 
2
Lab: 
0
Credits: 
2
ECTS: 
3
Course Language: 
English
Course Objectives: 
The aim of this course is to provide knowledge to pharmacy students about the general treatment principles of poisonings; mechanisms of toxic effects, toxicity symptoms, antidots and treatment protocols of drugs used extentively in clinics, toxic gases, abused drugs, pesticides, and household chemicals.
Course Content: 

In this course, general knowledge about clinical toxicology; toxic responses of target organs; general principles of treatment in poisonings; the toxicity of analgesic and antiinflammatory drugs, anticholinergic and neuroleptic drugs, abused drugs and substances, sympathomimetics, sedative aand hypnotics, cardiovascular drugs, hallusinogenic drugs and substances, toxic gases, pesticides (insecticides, rodenticides, and herbicides), alyphatic and aromatic hydrocarbons will be discussed.

Course Methodology: 
1: Anlatım, 2: Soru-Cevap, 3: Tartışma, 4. Sunum. 5:Simülasyon, 6:Video, 7:Uygulamalar, 8: Vaka çözümlemeleri 1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D:False and troth, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

Programme learning outcomes

Teaching Methods

Assessment Methods

1) Being able to understand the general principles of treatment in poisonings.

1, 2, 7, 14

1,2,3,6

A, B, C, D, G, H

2) Being able to understand the toxic responses of target organs.

5, 7,

1,2,3,6

A, B, C, D, G, H

3)  Being able to understand the toxicity mechanisms of drugs and other chemical and biological substances.

3, 4, 5, 7, 9, 11, 12, 14

1,2,3,6

A, B, C, D, G, H

4) Being able to understand the antidotes and treatment protocols for drugs, and other chemical and biological substances.

3, 5, 6, 7, 12, 14

1,2,3,6

A, B, C, D, G, H

5) Being able to use acquired knowledge for protection of human and environmental health.

3, 4, 8, 9, 13

1,2,3,6

A, B, C, D, G, H

 
 

Course Flow

Week

Teorical Topics                                      

Study Materials

1

Introduction to clinical toxicology-I

Study the sources.

2

Introduction to clinical toxicology-II

Study the sources.

3

Analgesic and anti-inflammatory agents

Study the sources.

4

Anticholinergic and neuroleptic drugs

Study the sources.

5

Opiates and opioids

Study the sources.

6

Sympathomimetics

Study the sources.

7

Sedative/hypnotics

Study the sources.

8

Cardiovascular drugs

Study the sources.

9

Hallusinogenic agents

Study the sources.

10

Toxic gases

Study the sources.

11

Insecticides

Study the sources.

12

Herbicides

Study the sources.

13

Rodenticides

Study the sources.

14

Aliphatic and aromatic hydrocarbons

Study the sources.

15

Household chemicals

Study the sources.

 
 

Recommended Sources

Textbook

  1. Barile, A.F. ‘Clinical Toxicology, Principles and Mechanisms’, CRC Press, London, 2004.
  2. Olson K.R., Lange Poisoning & Drug Overdose, Lange Medical Books/McGraw-Hill, 2007
  3. Claassen, C.D.,  Casarett and Doull’s Toxicology, McGraw-Hill Medical Publishing Division, 2008
  4. Brunton, L.L., Lazo, J.S., Parker, K.L.: Godman and Gilman’s The Pharmacological Basis Of Therapeutics, 11th Edition, McGraw Hill, New York, 2005

Additional Resources

Lecture notes

 
 

Material Sharing

Documents

Photocopy shareable.

Assignments

Shareable.

Exams

Not shareable.

 
 

Assessment

IN-TERM STUDIES

NUMBER

PERCENTAGE

Midterm  Exam

1

95

Quiz

-

-

Homework

1

5

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 

60

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

40

Total

 

100

 

 

COURSE CATEGORY

Compulsary

 
 

Course’s Contribution to Program

No

Program Learning Outcomes

Contribution

1

2

3

4

5

1

Acquire skills needed to practice the profession of pharmacy in either a Turkish or an English language setting.

       

X

2

Being equipped to access current theoretical and applied knowledge, keeping abreast of new developments, and possessing the critical faculties enabling an accurate and reliable interpretation and assessment of this information.

       

X

3

Having the capacity to apply the skills acquired in the field of pharmaceutical science. Possessing the ability to harness his/her acquired knowledge in order to function as a highly accessible health counsellor, providing a ready source of clinically relevant, health-related information to the general public.

       

X

4

Keeping abreast of and being equipped to apply the fundamental pharmaceutical and health science principles which guide future developments in modern technology, and being able to share these experiences and skills with colleagues through participatation in professional development education seminars.

     

X

 

5

Knowing how to assess risks arising from the use of drugs and other chemicals and those risks potentially encounterd during laboratory practice.

       

X

6

Acquiring the skills and knowledge needed to interpret findings obtained through quantative and qualitative measurements, and thus reach valid, scientific conclusions based on this data. 

 

X

     

7

Being able to compound pharmaceutical products while being knowledgable about their clinical application, interactions, side effects and risks  and apply in proper manner .

       

X

8

Being competent to conduct and manage research and development projects, and share experimental outcomes.

     

X

 

9

Be competent to accurately and intelligibly communicate clincally relevant information to patients concerning prescription items and other pharmaceutical products.  

       

X

10

Being able to function in a multidisciplinary environment. Possessing the skill to collaborate and establish lines of communication with other professionals, while developing their own professional competency through participation in relevant continuing education activities.

       

X

11

Being able to play a role in projects which fulfills the profession’s societal responsibilities. Participating in professional activities and undertaking duties in a manner which reflects an awareness of and sensitivity to environmental issues.

     

X

 

12

Being capable of opening a community pharmacy, practicing in a hospital pharmacy setting, and offering service in any field related to drugs, cosmetics, medical  and/or plant-derived products. Able to play an active role in his/her own personal professional development, as well as that of colleagues and pharmaceutical students.

       

X

13

Able to play a role in issues related to public health as a member of the health care team while being cognizant of and able to fulfill legal and professional requirements and maintain ethical standards. 

       

X

14

Is knowledgable of and equipped to manage the planning, development, compounding and quality control analysis of naturally occuring and synthetic medicines, while also being aware of the processes related to these products’ absorption, distribution, metabolism and excretion from the body.

       

X

 
 

ECTS

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

15

2

30

Hours for off-the-classroom study (Pre-study, practice)

15

2

30

Midterm Exams

1

10

10

Homework

1

5

5

Final

1

10

10

Total Work Load

 

 

90

Total Work Load / 25 (h)

 

 

3,4

ECTS Credit of the Course

 

 

3