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Course Code: 
MDP 221
Course Period: 
Autumn
Course Type: 
Core
P: 
3
Lab: 
0
Credits: 
3
ECTS: 
4
Course Language: 
English
Course Objectives: 
To teach the students organic molecules and elements of the human body, metabolisms of these constituents, energy production, interrelationships of the systems which control these metabolisms, pathological cases concerning the metabolisms.
Course Content: 

Definitions of enzymes, principles of enzymatic reactions, metabolisms of carbohydrates, proteins, lipids and energy release in these metabolisms, control of biochemical processes by hormones, nutritional compounds; vitamins and minerals, hemoglobin: functions, synthesis and degradation, xenobiotic metabolism.

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D:False and troth, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

Programme learning outcomes

Teaching Methods

Assessment Methods

1) Explains enzymatic principles of metabolic  

    reactions

1,14

1

A,B,C,D

2) Describes  energy  production 

1,14

1

A,B,C,D

3) Explains metabolic processes concerning        carbohydrates, proteins and lipids

1,14

1

A,B,C,D

4) Defines hormonal control of metabolic processes

1,14

1

A,B,C,D

5) Explains metabolic functions of vitamins and      minerals

1,14

1

A,B,C,D

6)  Decsribes functions, synthesis and degradation of hemoglobin as well as pathological conditions

1,14

1

A,B,C,D

7)  Defines xenobiotic metabolism

1,14

1

A,B,C,D

 
 

Course Flow

Week

Teorical Topics                                     

Lab content

Study Materials

1

Nucleotides significant for metabolic processes:  structures and functions

 

Textbook by Prof.Dr. İnci Özden

2

Enzymes:  principles of enzymatic reactions, functions of enzyme classes

 

Textbook by Prof.Dr. İnci Özden

3

ATP production:  energy conservation 

 

Textbook by Prof.Dr. İnci Özden

4

Carbohydrate metabolism:  Digestion and absorption, interrelationships between catabolic processes and energy production, anabolic processes concerning carbohydrates, pathological conditions related to carbohydrate metabolism

 

Textbook by Prof.Dr. İnci Özden

5

Lipid metabolism:  Digestion and absorption, interrelationships between catabolic processes and energy production, anabolic processes concerning lipids, pathological conditions related to lipid  metabolism

 

Textbook by Prof.Dr. İnci Özden

6

Protein metabolism:  Digestion and absorption, interrelationships between catabolic processes and energy production, anabolic processes concerning proteins, pathological conditions related to protein  metabolism

 

Textbook by Prof.Dr. İnci Özden

7

Hormones:  General mechanisms of actions of hormones, hormonal cascade starting from hypothalamus and hormones of the cascade, hormones of adrenal gland, hormones involved in calcium homeostasis, hormones of pancreas, hormones of gastrointestinal system.

 

Textbook by Prof.Dr. İnci Özden

8

Vitamins: Lipid-soluble and water-soluble vitamins, structures and functions, pathological cases concerning vitamin deficiencies.

 

Textbook by Prof.Dr. İnci Özden

9

Mineral:  Macrominerals, microminerals, functions, pathological cases in mineral deficiency conditions.

 

Textbook by Prof.Dr. İnci Özden

10

Hemoglobin:  structure, functions,  factors effecting oxygen transport, synthesis of hemoglobin, degradation of hemoglobin, hemoglobin variants, jaundice and hemoglobin degradation products, anemia.

 

Textbook by Prof.Dr. İnci Özden

11

Xenobiotic metabolism:  principles, phases involved, related enzymes.

 

Textbook by Prof.Dr. İnci Özden

12

Case Studies- group Work

 

 

13

Case Studies- group Work

 

 

14

Take home work: Case solutions

 

 
 
 

Recommended Sources

Textbook

Prof.Dr. İnci Özden’s Biochemistry Textbook  prepared for Yeditepe University Faculty of Pharmacy Students

Additional Resources

1.         Harper’s Illustrated Bichemistry,R.K.Murray, D.A.Bender, K.M.Botham, V.W.Rodwell, P.A. Weil,McGrawHill, 2009

2.         Lippincot’s Illustrated Reviews, Biochemistry, P.C. Champ, R.A.Harvey, D,R, Ferrier, LWW, 2008

3.          Eczacılık Fakültesi Öğrencileri için Biokimya Dersleri, Porf.Dr.Ayşe Can, Prof.Dr. Nuriye Akev, İ.Ü.Yayınları, 2008

 
 

Material Sharing

Documents

Prof.Dr. İnci Özden’s Biochemistry Textbook  prepared for Yeditepe University Faculty of Pharmacy Students

Assignments

None

Exams

A midterm exam, final exam and make-up exam for failing students

 

 

 

Assessment

IN-TERM STUDIES

NUMBER

PERCENTAGE

Midterm  Exam

1

40

Short Exam

   

Assignment

 

 

Total

 

100

CONTRIBUTION OF FINAL (Final- Make Up) EXAMINATION TO OVERALL GRADE

 

60

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

40

Total

 

100

 

 

 

 

COURSE CATEGORY

Compulsary

 
 

Course’s Contribution to Program

No

Program Learning Outcomes

Contribution

1

2

3

4

5

 

1

Acquire skills needed to practice the profession of pharmacy in either a Turkish or an English language setting.

   

X

     

2

Being equipped to access current theoretical and applied knowledge, keeping abreast of new developments, and possessing the critical faculties enabling an accurate and reliable interpretation and assessment of this information.

   

 

 

   

3

Having the capacity to apply the skills acquired in the field of pharmaceutical science. Possessing the ability to harness his/her acquired knowledge in order to function as a highly accessible health counsellor, providing a ready source of clinically relevant, health-related information to the general public.

   

 

 

   

4

Keeping abreast of and being equipped to apply the fundamental pharmaceutical and health science principles which guide future developments in modern technology, and being able to share these experiences and skills with colleagues through participatation in professional development education seminars.

   

 

     

5

Knowing how to assess risks arising from the use of drugs and other chemicals and those risks potentially encounterd during laboratory practice.

           

6

Acquiring the skills and knowledge needed to interpret findings obtained through quantative and qualitative measurements, and thus reach valid, scientific conclusions based on this data. 

           

7

Being able to compound pharmaceutical products while being knowledgable about their clinical application, interactions, side effects and risks  and apply in proper manner .

           

8

Being competent to conduct and manage research and development projects, and share experimental outcomes.

           

9

Be competent to accurately and intelligibly communicate clincally relevant information to patients concerning prescription items and other pharmaceutical products.  

           

10

Being able to function in a multidisciplinary environment. Possessing the skill to collaborate and establish lines of communication with other professionals, while developing their own professional competency through participation in relevant continuing education activities.

   

 

     

11

Being able to play a role in projects which fulfills the profession’s societal responsibilities. Participating in professional activities and undertaking duties in a manner which reflects an awareness of and sensitivity to environmental issues.

           

12

Being capable of opening a community pharmacy, practicing in a hospital pharmacy setting, and offering service in any field related to drugs, cosmetics, medical  and/or plant-derived products. Able to play an active role in his/her own personal professional development, as well as that of colleagues and pharmaceutical students.

           

13

Able to play a role in issues related to public health as a member of the health care team while being cognizant of and able to fulfill legal and professional requirements and maintain ethical standards. 

           

14

Is knowledgable of and equipped to manage the planning, development, compounding and quality control analysis of naturally occuring and synthetic medicines, while also being aware of the processes related to these products’ absorption, distribution, metabolism and excretion from the body.

     

X

   
 
 

ECTS

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

16

3

48

Hours for off-the-classroom study (Pre-study, practice)

16

3

48

Midterm Exams

1

5

5

Lab. Applications

 

   

Hours for off-the-Lab. study (Pre-study, practice)

 

   

Lab. Midterm Exem

     

Lab. Final

     

Homework

 

 

 

Final

1

10

10

Total Work Load

 

 

111

Total Work Load / 25 (h)

 

 

4,04

ECTS Credit of the Course

 

 

4