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Course Code: 
PHAR 431
Course Period: 
Autumn
Course Type: 
Core
P: 
2
Lab: 
0
Credits: 
2
ECTS: 
3
Course Language: 
English
Course Coordinator: 
Serdar ÖZTEZCAN
Courses given by: 
Serdar ÖZTEZCAN
Jale ÇOBAN
Course Objectives: 
A central function of the clinical chemistry laboratory is to provide biochemical information for the management of patients. Such information will be of value only if it is accurate and relevant, and if its significance is appreciated by the clinician so that it can be used appropriately to guide clinical decision-making. These lectures examine how biochemical data are acquired and how they should be used.
Course Content: 

Definitions of clinical biochemistry, regulation of glucose concentration in the body, markers of cardiac injury, metabolism of cholesterol and threeglyceride, mechanisms incolved in the regulation of hormone secretion, enzymes that can be used to detect diseases, tests of liver injury, tests of kidney injury, diagnostically important plasma proteins, Tumor markers, basic tests in hematological disorders, common methods in blood analysis and the parameters of complete blood count.

Course Methodology: 
1: Lecture, 2: Question-Answer, 3: Discussion, 4: Presentation, 5:Simulation, 6: Video, 7: Applications, 8:Case Study
Course Evaluation Methods: 
A:Written exam, B: multiple chose , C:Filing the blank D:False and troth, E: Oral Exam F: Portfolio, G: Contrabution of course activities H:Homework

Vertical Tabs

Course Learning Outcomes

Learning Outcomes

Programme learning outcomes

Teaching Methods

Assessment Methods

1.Explains the types of specimens that are routinely and nonroutinely collected for testing and the advantages and disadvantages of each.

1,14

1

A,B,C,D

2.Explains the laboratory procedures involved in assessment of diabetes mellitus in a individual .

1,14

1

A,B,C,D

3.Explains the key markers of cardiac injury and their order of appearance after a myocardial infarction

1,14

1

A,B,C,D

4.Discuss the metabolism of cholesterol and threeglyceride and state the reference interval of each for apparently healtyh subjects.

1,14

1

A,B,C,D

5.Defines physiological functions of hormones and discuss the mechanisms incolved in the regulation of hormone secretion

1,14

1

A,B,C,D

6.Discuss the role of clinical importance of enzymes in the diagnosis and treatment of diseases.

1,14

1

A,B,C,D

7.Discuss common sources of discrepancies in patient liver function, enzyme test results and discuss situations when it is important to communicate bilirubin results to health care providers.

1,14

1

A,B,C,D

8.Discuss the test of kidney injury

1,14

   1

A,B,C,D

9.Learn the abnormalities of diagnostically important plasma proteins, clinical indications for assessment of acute phase proteins and the major clinical use of serum and urine protein electrophoresis.

1,14

1

A,B,C,D
10. Associate Tumor markers of disease with the organ or tissue location of the disease.

 

1

 A,B,C,D
11. Learn common clinical disorders associated with abnormal haemostasis and experience the interpretation of patient results in a variety of clinical settings.

 

 1 A,B,C,D
12.Describe the cause of anemia and give examples for the test that are used to assess the diagnosis of this disease.

 

 1 A,B,C,D
 

Course Flow

COURSE CONTENT

Week

Teorical Topics                                     

Study Materials

1

 Introduction to Clinical Biochemistry

Textbook by Prof.Dr. Serdar Öztezcan

2

Carbohyrates in clinical biochemistry

Textbook by Prof.Dr Serdar Öztezcan

3

Heart Diseases and Cardiac Markers

Textbook by Prof.Dr. Serdar Öztezcan

4

Lipids and Lipoproteins

Textbook by Prof.Dr. Serdar Öztezcan

5

Hormones in clinical biochemistry

Textbook by Prof.Dr. Serdar Öztezcan

6

Clinical Enzymology

Textbook by Assoc.Prof.Dr. Jale Çoban

7

Liver function tests

Textbook by Assoc.Prof.Dr. Jale Çoban

8

Renal function tests

Textbook by Assoc.Prof.Dr. Jale Çoban

9

Spesicic Proteins

Textbook by Assoc.Prof.Dr. Jale Çoban

10

Tumor markers

Textbook by Assoc.Prof.Dr. Jale Çoban

11

Coagulation and Fibrinolysis

Textbook by Assoc.Prof.Dr. Jale Çoban

12

Hematology and Complete Blood Count test

Textbook by Assoc.Prof.Dr. Jale Çoban

13

Case Studies- group Work

  

14

Take home work: Case solutions

  
 

Recommended Sources

RECOMMENDED SOURCES

Textbook

Prof.Dr. Serdar Öztezcan’s and Assoc.Prof.Dr.Jale Çoban’s cours  note’s prepared for Yeditepe University Faculty of Pharmacy Students

Additional Resources

1.Harper’s Illustrated Bichemistry,R.K.Murray, D.A.Bender, K.M.Botham, V.W.Rodwell, P.A. Weil,McGrawHill, 2009

2.Lippincot’s Illustrated Reviews, Biochemistry, P.C. Champ, R.A.Harvey, D,R, Ferrier, LWW, 2008

3.  Henry’s Clinical Diagnosis and Management by Laboratory Methods
 
 
 

Material Sharing

MATERIAL SHARING

Documents

Course note’s by Prof.Dr.Serdar Öztezcan’s and Assoc.Prof.Dr. Jale Çoban ‘s prepared for Yeditepe University Faculty of Pharmacy Students

Assignments

None

Exams

A midterm exam, final exam and make-up exam for failing students
 
 
 

Assessment

ASSESSMENT

IN-TERM STUDIES

NUMBER

PERCENTAGE

Midterm  Exam

1

40

Final Exam

1

60

Make-up Exam for students failing by the end of Final Exam

1

60

Total

 

100

CONTRIBUTION OF FINAL EXAMINATION TO OVERALL GRADE

 

60

CONTRIBUTION OF IN-TERM STUDIES TO OVERALL GRADE

 

40

Total

 

100
 

 

COURSE CATEGORY

Compulsary
 

Course’s Contribution to Program

COURSE'S CONTRIBUTION TO PROGRAM

No

Program Learning Outcomes

Contribution

1

2

3

4

5

1

Has national and international up-to-date, theoretical and applied knowledge in the field of pharmacy.

    

x

    

2

Defines problems related to the profession, collects data, evaluates its accuracy and reliability, develops evidence-based solutions, shares them with healthcare professionals, makes necessary explanations to other people.

    

 

x

  

3

Communicates accurately and effectively in accordance with cultural and ethical values with all relevant professional groups, especially those working in the field of health, and all segments of society, using information and communication technologies.

    

 

x

  

4

Takes into account the law and ethics when dealing with public health issues.

    

 

x

  

5

Acts as a pharmacist with high career awareness, self-confidence, leadership spirit, who is prone to teamwork, entrepreneurial, productive and able to manage financial resources.

  

x

      

6

Based on the principle of pharmaceutical care, Acts as an easily accessible health consultant with a patient-oriented approach and plays an active role in constantly informing the society.

        

x

7

Improves his/her knowledge by participating in in-service training and activities in line with the needs of the century and society, takes part in the professional development of colleagues and adopts the lifelong learning principle.

      

x

  

8

Suggests and manages multidisciplinary / interdisciplinary research and development projects related to pharmaceuticals, cosmetics, medical devices and shares their results.

  

x

      

9

Applies knowledge and skills for the benefits of the society taking part in social responsibility projects.

      

x

  

10

Fulfills the requirements of quality management systems using the theoretical and applied knowledge acquired in the field.

  

x

 

    
 
 

ECTS

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities

Quantity

Duration
(Hour)

Total
Workload
(Hour)

Course Duration (Including the exam week: 16x Total course hours)

12

2

24

Hours for off-the-classroom study (Pre-study, practice)

16

3

48

Midterm Exams

1

5

5

Lab. Applications

 

    

Hours for off-the-Lab. study (Pre-study, practice)

 

    

Lab. Midterm Exem

      

Lab. Final

      

Homework

 

 

 

Final

1

    

Total Work Load

 

 

111

Total Work Load / 25 (h)

 

 

4,04

ECTS Credit of the Course

 

 

4
 
 
 
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